PDBe 4hyy

X-ray diffraction
2.6Å resolution

Filament of octameric rings of DMC1 recombinase from Homo sapiens

Released:
Source organism: Homo sapiens
Primary publication:
Structure of a filament of stacked octamers of human DMC1 recombinase.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 69 382-6 (2013)
PMID: 23545642

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo octamer (preferred)
homo 16-mer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Meiotic recombination protein DMC1/LIM15 homolog Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 265 amino acids
Theoretical weight: 29.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q14565 (Residues: 84-340; Coverage: 76%)
Gene names: DMC1, DMC1H, LIM15
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P4
Unit cell:
a: 123.997Å b: 123.997Å c: 91.713Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.179 0.246
Expression system: Escherichia coli BL21(DE3)