PDBe 4hni

X-ray diffraction
2.74Å resolution

crystal structure of ck1e in complex with PF4800567

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Casein kinase I isoform epsilon Chains: A, B
Molecule details ›
Chains: A, B
Length: 296 amino acids
Theoretical weight: 34.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P49674 (Residues: 1-294; Coverage: 71%)
Gene name: CSNK1E
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P43212
Unit cell:
a: 111.108Å b: 111.108Å c: 155.426Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.237 0.273
Expression system: Escherichia coli