Function and Biology

Crystal structure of glutathione transferase homolog from drosophilia mojavensis, TARGET EFI-501819, with bound glutathione

Source organism: Drosophila mojavensis
Biochemical function: glutathione transferase activity
Biological process: glutathione metabolic process
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00043
Domain description: Glutathione S-transferase, C-terminal domain
Occurring in:
  1. Glutathione transferase
The deposited structure of PDB entry 4hi7 contains 2 copies of Pfam domain PF00043 (Glutathione S-transferase, C-terminal domain) in Glutathione transferase. Showing 1 copy in chain A.

PF13417
Domain description: Glutathione S-transferase, N-terminal domain
Occurring in:
  1. Glutathione transferase
The deposited structure of PDB entry 4hi7 contains 2 copies of Pfam domain PF13417 (Glutathione S-transferase, N-terminal domain) in Glutathione transferase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR004045
Domain description: Glutathione S-transferase, N-terminal
Occurring in:
  1. Glutathione transferase
IPR004046
Domain description: Glutathione S-transferase, C-terminal
Occurring in:
  1. Glutathione transferase
IPR010987
Domain description: Glutathione S-transferase, C-terminal-like
Occurring in:
  1. Glutathione transferase
IPR036282
Domain description: Glutathione S-transferase, C-terminal domain superfamily
Occurring in:
  1. Glutathione transferase
IPR040079
Domain description: Glutathione transferase family
Occurring in:
  1. Glutathione transferase
IPR036249
Domain description: Thioredoxin-like superfamily
Occurring in:
  1. Glutathione transferase

Structure domains

CATH CATH domains
1.20.1050.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
Homology: Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
Occurring in:
  1. Glutathione transferase
The deposited structure of PDB entry 4hi7 contains 2 copies of CATH domain 1.20.1050.10 (Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2) in Glutathione transferase. Showing 1 copy in chain A.
3.40.30.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Glutaredoxin
Homology: Glutaredoxin
Occurring in:
  1. Glutathione transferase
The deposited structure of PDB entry 4hi7 contains 2 copies of CATH domain 3.40.30.10 (Glutaredoxin) in Glutathione transferase. Showing 1 copy in chain A.