› 4hi7

X-ray diffraction
1.25Å resolution

Crystal structure of glutathione transferase homolog from drosophilia mojavensis, TARGET EFI-501819, with bound glutathione

Released:
DOI: 10.2210/pdb4hi7/pdb
PDB 4hi7 coloured by chain and viewed from the front.
PDB 4hi7 coloured by chain and viewed from the side.
PDB 4hi7 coloured by chain and viewed from the top.
Source organism: Drosophila mojavensis
Entry authors: Vetting MW, Toro R, Bhosle R, Al Obaidi NF, Morisco LL, Wasserman SR, Sojitra S, Washington E, Scott Glenn A, Chowdhury S, Evans B, Hammonds J, Hillerich B, Love J, Seidel RD, Imker HJ, Armstrong RN, Gerlt JA, Almo SC, Enzyme Function Initiative (EFI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GI20122 Chains: A, B
Molecule details ›
Chains: A, B
Length: 228 amino acids
Theoretical weight: 25.56 KDa
Source organism: Drosophila mojavensis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: B4KM86 (Residues: 1-221; Coverage: 100%)
Gene names: Dmoj\GI20122, Dmoj_GI20122
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand GSH 2 x GSH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P3121
Unit cell:
a: 50.7Å b: 50.7Å c: 289.473Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.2 0.228
Expression system: Escherichia coli BL21(DE3)

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