PDBe 4hfx

X-ray diffraction
2.54Å resolution

Crystal structure of a transcription elongation factor B polypeptide 3 from Homo sapiens, Northeast Structural Genomics consortium target id HR4748B.

Released:
Source organism: Homo sapiens
Entry authors: Seetharaman J, Su M, Ciccosanti C, Sahdev S, Acton TB, Xiao R, Everett JK, Montelione GT, Hunt JF, Tong L, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Elongin-A Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 97 amino acids
Theoretical weight: 12.14 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q14241 (Residues: 597-682; Coverage: 11%)
Gene names: ELOA, MSTP059, TCEB3

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P31
Unit cell:
a: 80.643Å b: 80.643Å c: 63.222Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.236 0.235 0.263