X-ray diffraction
1.7Å resolution

Crystal structure of native human MAdCAM-1 D1D2 domain

Source organism: Homo sapiens
Entry authors: Springer T, Yu Y, Zhu J

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Mucosal addressin cell adhesion molecule 1 Chain: A
Molecule details ›
Chain: A
Length: 209 amino acids
Theoretical weight: 22.35 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
  • Canonical: Q13477 (Residues: 23-225; Coverage: 56%)
Gene name: MADCAM1
Sequence domains: Adhesion molecule, immunoglobulin-like
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2221
Unit cell:
a: 64.476Å b: 99.988Å c: 69.668Å
α: 90° β: 90° γ: 90°
R R work R free
0.177 0.171 0.214
Expression system: Cricetulus griseus