PDBe 4h2g

X-ray diffraction
1.55Å resolution

Human ecto-5'-nucleotidase (CD73): crystal form II (open) in complex with adenosine


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
5'-nucleotidase Chain: A
Molecule details ›
Chain: A
Length: 546 amino acids
Theoretical weight: 60.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P21589 (Residues: 27-549; Coverage: 95%)
Gene names: NT5, NT5E, NTE
Sequence domains:
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P21212
Unit cell:
a: 67.1Å b: 131Å c: 66.01Å
α: 90° β: 90° γ: 90°
R R work R free
0.129 0.129 0.18
Expression system: Escherichia coli