Structure analysis

Human ARTD1 (PARP1) - Catalytic domain in complex with inhibitor ME0328

X-ray diffraction
2.89Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: monomeric

Binding statistics and energies are not available for this assembly
Assembly 2
Download    3D Visualisation
Multimeric state: monomeric

Binding statistics and energies are not available for this assembly
Assembly 3
Download    3D Visualisation
Multimeric state: monomeric

Binding statistics and energies are not available for this assembly
Assembly 4
Download    3D Visualisation
Multimeric state: monomeric
Accessible surface area: 16700 Å2
Buried surface area: 400 Å2
Dissociation area: 200 Å2
Dissociation energy (ΔGdiss): 2 kcal/mol
Dissociation entropy (TΔSdiss): 2 kcal/mol
Interface energy (ΔGint): -3 kcal/mol
Symmetry number: 1

Macromolecules

Search similar proteins