Structure analysis

Structure of unliganded, inactive Ror2 kinase domain

X-ray diffraction
2.406Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
Accessible surface area: 13500 Å2
Buried surface area: 400 Å2
Dissociation area: 100 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Interface energy (ΔGint): 2 kcal/mol
Symmetry number: 1
Assembly 2
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Multimeric state: monomeric
Accessible surface area: 13300 Å2
Buried surface area: 400 Å2
Dissociation area: 100 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Interface energy (ΔGint): 2 kcal/mol
Symmetry number: 1

Macromolecules

Chains: A, B
Length: 308 amino acids
Theoretical weight: 35.46 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q01974 (Residues: 452-753; Coverage: 33%)
Gene names: NTRKR2, ROR2
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
CATH:

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