4gfx

X-ray diffraction
1.6Å resolution

Crystal structure of the N-terminal domain of TXNIP

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin-interacting protein Chain: A
Molecule details ›
Chain: A
Length: 151 amino acids
Theoretical weight: 17.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H3M7 (Residues: 4-154; Coverage: 39%)
  • Best match: Q9H3M7-2 (Residues: 27-99)
Gene names: TXNIP, VDUP1
Sequence domains: Arrestin (or S-antigen), N-terminal domain
Structure domains: Immunoglobulin-like

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: P212121
Unit cell:
a: 37.431Å b: 56.621Å c: 67.66Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.171 0.227
Expression system: Escherichia coli