4gcp

X-ray diffraction
1.98Å resolution

Crystal Structure of E. coli OmpF porin in complex with Ampicillin

Released:
Source organism: Escherichia coli K-12
Primary publication:
The binding of antibiotics in OmpF porin.
Structure 21 76-87 (2013)
PMID: 23201272

Function and Biology Details

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer membrane porin F Chains: A, B
Molecule details ›
Chains: A, B
Length: 341 amino acids
Theoretical weight: 37.17 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P02931 (Residues: 23-362; Coverage: 100%)
Gene names: JW0912, b0929, cmlB, coa, cry, ompF, tolF
Sequence domains: Gram-negative porin
Structure domains: Porin

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P3
Unit cell:
a: 116.6Å b: 116.6Å c: 53.27Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.203 0.239
Expression system: Escherichia coli