Assemblies
Assembly Name:
Histidine--tRNA ligase, cytoplasmic
Multimeric state:
homo dimer
Accessible surface area:
36862.66 Å2
Buried surface area:
7558.92 Å2
Dissociation area:
3,779.46
Å2
Dissociation energy (ΔGdiss):
51.87
kcal/mol
Dissociation entropy (TΔSdiss):
15.43
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-146096
Macromolecules
Chains: A, B
Length: 517 amino acids
Theoretical weight: 58.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
InterPro:
Length: 517 amino acids
Theoretical weight: 58.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P12081 (Residues: 1-506; Coverage: 99%)
Pfam:
InterPro:
- WHEP-TRS domain
- uS15/NS1, RNA-binding domain superfamily
- Aminoacyl-tRNA synthetase, class II
- Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)
- Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit
- Histidine-tRNA ligase
- Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain
- Anticodon-binding domain superfamily
- Histidyl-anticodon-binding
- Anticodon-binding
