PDBe 4g1t

X-ray diffraction
2.8Å resolution

Crystal structure of interferon-stimulated gene 54

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interferon-induced protein with tetratricopeptide repeats 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 472 amino acids
Theoretical weight: 54.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09913 (Residues: 1-472; Coverage: 100%)
Gene names: CIG-42, G10P2, IFI54, IFIT2, ISG54
Sequence domains: Tetratricopeptide repeat
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U, PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P212121
Unit cell:
a: 80.023Å b: 95.207Å c: 155.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.234 0.287
Expression system: Escherichia coli