› 4g19

X-ray diffraction
2Å resolution

Crystal structure of the glutathione transferase GTE1 from Phanerochaete chrysosporium in complex with glutathione

Released:
DOI: 10.2210/pdb4g19/pdb
PDB entry 4g19 coloured by chain, front view.
PDB entry 4g19 coloured by chain, side view.
PDB entry 4g19 coloured by chain, top view.
Source organism: Phanerodontia chrysosporium
Primary publication:
Characterization of a Phanerochaete chrysosporium glutathione transferase reveals a novel structural and functional class with ligandin properties.
Mathieu Y, Prosper P, Buée M, Dumarçay S, Favier F, Gelhaye E, Gérardin P, Harvengt L, Jacquot JP, Lamant T, Meux E, Mathiot S, Didierjean C, Morel M
J Biol Chem 287 39001-11 (2012)
PMID: 23007392

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125223 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GST N-terminal domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 253 amino acids
Theoretical weight: 28.88 KDa
Source organism: Phanerodontia chrysosporium
Expression system: Escherichia coli
UniProt:
  • Canonical: I6ZUH3 (Residues: 1-253; Coverage: 100%)
Sequence domains: Glutathione S-transferase, N-terminal domain
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand ACT 6 x ACT
Ligand GSH 4 x GSH
Ligand GOL 7 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P212121
Unit cell:
a: 86.573Å b: 88.146Å c: 156.49Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.177 0.22
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The still mysterious roles of cysteine-containing glutathione transferases in plants.
Lallement et al. (2014)
1 more

3 mentions without citation

Diversification of fungal specific class a glutathione transferases in saprotrophic fungi.
Mathieu et al. (2013)
2 more