Assemblies
Multimeric state:
hetero trimer
Accessible surface area:
29826.05 Å2
Buried surface area:
2386.69 Å2
Dissociation area:
1,047.7
Å2
Dissociation energy (ΔGdiss):
-3.45
kcal/mol
Dissociation entropy (TΔSdiss):
19.21
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-192830
Macromolecules
Chain: A
Length: 328 amino acids
Theoretical weight: 38.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Mo25-like
InterPro:
CATH: Leucine-rich Repeat Variant
Length: 328 amino acids
Theoretical weight: 38.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9Y376 (Residues: 11-334; Coverage: 95%)
Pfam: Mo25-like
InterPro:
CATH: Leucine-rich Repeat Variant
Chain: B
Length: 283 amino acids
Theoretical weight: 31.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Protein kinase domain
InterPro:
Length: 283 amino acids
Theoretical weight: 31.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9P289 (Residues: 18-297; Coverage: 67%)
Pfam: Protein kinase domain
InterPro:
- MST4, kinase domain
- Protein kinase-like domain superfamily
- Protein kinase domain
- Protein kinase, ATP binding site
- Serine-threonine/tyrosine-protein kinase, catalytic domain
Chain: C
Length: 5 amino acids
Theoretical weight: 669 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 5 amino acids
Theoretical weight: 669 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: Q9P289 (Residues: 323-327; Coverage: 1%)