› 4fxq

X-ray diffraction
1.96Å resolution

Full-length Certhrax toxin from Bacillus cereus in complex with Inhibitor P6

Released:
DOI: 10.2210/pdb4fxq/pdb
PDB entry 4fxq coloured by chain, front view.
PDB entry 4fxq coloured by chain, side view.
PDB entry 4fxq coloured by chain, top view.
Source organism: Bacillus cereus
Primary publication:
Certhrax toxin, an anthrax-related ADP-ribosyltransferase from Bacillus cereus.
Visschedyk D, Rochon A, Tempel W, Dimov S, Park HW, Merrill AR
J Biol Chem 287 41089-102 (2012)
PMID: 22992735

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175654 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative ADP-ribosyltransferase Certhrax Chains: A, B
Molecule details ›
Chains: A, B
Length: 460 amino acids
Theoretical weight: 53.57 KDa
Source organism: Bacillus cereus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q4MV79 (Residues: 18-471; Coverage: 95%)
Gene name: BCE_G9241_pBC218_0027
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand G9L 2 x G9L
Ligand CL 3 x CL
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P212121
Unit cell:
a: 61.31Å b: 100.29Å c: 191.09Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.187 0.227
Expression system: Escherichia coli

Quick links

Citations

8 review citations

The Bacillus cereus Group: Bacillus Species with Pathogenic Potential.
Ehling-Schulz et al. (2019)
7 more

1 mention without citation

Certhrax toxin, an anthrax-related ADP-ribosyltransferase from Bacillus cereus.
Visschedyk et al. (2012)