4fu3

X-ray diffraction
1.9Å resolution

CID of human RPRD1B

Released:
Source organism: Homo sapiens
Entry authors: Ni Z, Xu C, Tempel W, El Bakkouri M, Loppnau P, Guo X, Bountra C, Arrowsmith CH, Edwards AM, Min J, Greenblatt JF, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulation of nuclear pre-mRNA domain-containing protein 1B Chains: A, B
Molecule details ›
Chains: A, B
Length: 135 amino acids
Theoretical weight: 15.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9NQG5 (Residues: 2-135; Coverage: 41%)
Gene names: C20orf77, CREPT, RPRD1B
Sequence domains: RNA polymerase II-binding domain.
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: C2221
Unit cell:
a: 57.752Å b: 79.784Å c: 108.666Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.209 0.259
Expression system: Escherichia coli BL21