4ftb

X-ray diffraction
2.7Å resolution

Crystal structure of the authentic Flock House virus particle

Released:
Source organism: Flock House virus
Entry authors: Speir JA, Chen Z, Reddy VS, Johnson JE

Function and Biology Details

Reaction catalysed:
Hydrolysis of an asparaginyl bond involved in the maturation of the structural protein of the virus, typically -Asn-|-Ala- or -Asn-|-Phe-.
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero 420-mer (preferred)
hetero heptamer
hetero 35-mer
hetero 42-mer
hetero 140-mer
Entry contents:
2 distinct polypeptide molecules
1 distinct RNA molecule
Macromolecules (3 distinct):
Capsid protein beta Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 363 amino acids
Theoretical weight: 39.37 KDa
Source organism: Flock House virus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P12870 (Residues: 1-363; Coverage: 89%)
Gene name: alpha
Structure domains: Jelly Rolls
Peptide gamma Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 44 amino acids
Theoretical weight: 4.4 KDa
Source organism: Flock House virus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P12870 (Residues: 364-407; Coverage: 11%)
Gene name: alpha
Flock House virus genomic RNA Chain: R
Molecule details ›
Chain: R
Length: 15 nucleotides
Theoretical weight: 4.57 KDa

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: R3
Unit cell:
a: 327.66Å b: 327.66Å c: 774.49Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.24 0.24 not available
Expression system: Drosophila melanogaster