› 4fs0

X-ray diffraction
3.25Å resolution

Crystal structure of mutant F136D of mouse nectin-2 extracellular fragment D1-D2

Released:
DOI: 10.2210/pdb4fs0/pdb
PDB entry 4fs0 coloured by chain, front view.
PDB entry 4fs0 coloured by chain, side view.
PDB entry 4fs0 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Nectin ectodomain structures reveal a canonical adhesive interface.
Harrison OJ, Vendome J, Brasch J, Jin X, Hong S, Katsamba PS, Ahlsen G, Troyanovsky RB, Troyanovsky SM, Honig B, Shapiro L
Nat Struct Mol Biol 19 906-15 (2012)
PMID: 22902367

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152345 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Nectin-2 Chain: A
Molecule details ›
Chain: A
Length: 225 amino acids
Theoretical weight: 24.89 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P32507 (Residues: 32-250; Coverage: 44%)
Gene names: Mph, Nectin2, Pvr, Pvrl2, Pvs
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: P6522
Unit cell:
a: 59.857Å b: 59.857Å c: 210.013Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.25 0.24 0.335
Expression system: Homo sapiens

Quick links

Citations

17 review citations

Mechanobiology of collective cell behaviours.
Ladoux et al. (2017)
16 more

1 mention without citation

Nectin ectodomain structures reveal a canonical adhesive interface.
Harrison et al. (2012)