PDBe 4fgf

X-ray diffraction
1.6Å resolution

REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor 2 Chain: A
Molecule details ›
Chain: A
Length: 146 amino acids
Theoretical weight: 16.44 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P09038 (Residues: 143-288; Coverage: 51%)
Gene names: FGF2, FGFB
Sequence domains: Fibroblast growth factor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P1
Unit cell:
a: 30.9Å b: 33.4Å c: 35.9Å
α: 59.5° β: 72° γ: 75.6°
R-values:
R R work R free
0.161 not available not available
Expression system: Not provided