4fgb

X-ray diffraction
2.6Å resolution

Crystal structure of human calcium/calmodulin-dependent protein kinase I apo form

Released:
Source organism: Homo sapiens
Entry authors: Zha M, Zhong C, Ou Y, Wang J, Han L, Ding J

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent protein kinase type 1 Chain: A
Molecule details ›
Chain: A
Length: 320 amino acids
Theoretical weight: 36.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14012 (Residues: 1-320; Coverage: 87%)
Gene name: CAMK1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2
Unit cell:
a: 91.046Å b: 67.7Å c: 56.138Å
α: 90° β: 99.75° γ: 90°
R-values:
R R work R free
0.25 0.248 0.299
Expression system: Escherichia coli