› 4euo

X-ray diffraction
1.28Å resolution

Structure of Atu4243-GABA sensor

Released:
DOI: 10.2210/pdb4euo/pdb
PDB entry 4euo coloured by chain, front view.
PDB entry 4euo coloured by chain, side view.
PDB entry 4euo coloured by chain, top view.
Source organism: Agrobacterium fabrum str. C58
Primary publication:
Structural basis for selective GABA binding in bacterial pathogens.
Planamente S, Mondy S, Hommais F, Vigouroux A, Moréra S, Faure D
Mol Microbiol 86 1085-99 (2012)
PMID: 23043322

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108859 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ABC transporter, substrate binding protein (Polyamine) Chain: A
Molecule details ›
Chain: A
Length: 320 amino acids
Theoretical weight: 35.15 KDa
Source organism: Agrobacterium fabrum str. C58
Expression system: Escherichia coli
UniProt:
  • Canonical: A9CGA5 (Residues: 23-336; Coverage: 100%)
Gene name: Atu4243
Sequence domains: Bacterial extracellular solute-binding protein
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

3 bound ligands:
Ligand GOL 3 x GOL
Ligand ABU 1 x ABU
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P3221
Unit cell:
a: 59.09Å b: 59.09Å c: 150.5Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.167 0.165 0.181
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Quorum quenching: role in nature and applied developments.
Grandclément et al. (2016)
5 more

3 mentions without citation

Determination of Ligand Profiles for Pseudomonas aeruginosa Solute Binding Proteins.
Fernández et al. (2019)
2 more