4esq

X-ray diffraction
1.7Å resolution

Crystal structure of the extracellular domain of PknH from Mycobacterium tuberculosis

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase PknH Chain: A
Molecule details ›
Chain: A
Length: 194 amino acids
Theoretical weight: 20.66 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P9WI71 (Residues: 435-626; Coverage: 31%)
Gene names: MTCY50.16, Rv1266c, pknH
Sequence domains: PknH-like extracellular domain
Structure domains: Protein Transport Mog1p; Chain A

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P21
Unit cell:
a: 47.455Å b: 35.923Å c: 49.308Å
α: 90° β: 98.36° γ: 90°
R-values:
R R work R free
0.165 0.163 0.197
Expression system: Escherichia coli BL21