X-ray diffraction
2.8Å resolution

Crystal structure of oxidized human nm23-H1

Source organism: Homo sapiens
Primary publication:
Structure of Nm23-H1 under oxidative conditions.
Acta Crystallogr. D Biol. Crystallogr. 69 669-80 (2013)
PMID: 23519676

Function and Biology Details

Reaction catalysed:
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Nucleoside diphosphate kinase A Chains: A, B
Molecule details ›
Chains: A, B
Length: 152 amino acids
Theoretical weight: 17.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P15531 (Residues: 1-152; Coverage: 100%)
Gene names: NDPKA, NM23, NME1
Sequence domains: Nucleoside diphosphate kinase
Structure domains: Nucleoside diphosphate kinase-like domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: P213
Unit cell:
a: 106.768Å b: 106.768Å c: 106.768Å
α: 90° β: 90° γ: 90°
R R work R free
0.19 0.182 0.256
Expression system: Escherichia coli