Function and Biology

Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-benzylguanine

Source organisms:
Biochemical function: O6-alkylguanine-DNA binding
Biological process: global genome nucleotide-excision repair
Cellular component: cytosol

Sequence family

Pfam Protein family (Pfam)
PF01035
Domain description: 6-O-methylguanine DNA methyltransferase, DNA binding domain
Occurring in:
  1. Alkyltransferase-like protein 1
The deposited structure of PDB entry 4enm contains 1 copy of Pfam domain PF01035 (6-O-methylguanine DNA methyltransferase, DNA binding domain) in Alkyltransferase-like protein 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR014048
Domain description: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding
Occurring in:
  1. Alkyltransferase-like protein 1
IPR036217
Domain description: Methylated DNA-protein cysteine methyltransferase, DNA binding domain
Occurring in:
  1. Alkyltransferase-like protein 1
IPR036388
Domain description: Winged helix-like DNA-binding domain superfamily
Occurring in:
  1. Alkyltransferase-like protein 1

Structure domain

CATH CATH domain
1.10.10.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Occurring in:
  1. Alkyltransferase-like protein 1
The deposited structure of PDB entry 4enm contains 1 copy of CATH domain 1.10.10.10 (Arc Repressor Mutant, subunit A) in Alkyltransferase-like protein 1. Showing 1 copy in chain A.