› 4emv

X-ray diffraction
1.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164436 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA topoisomerase IV, B subunit Chain: A
Molecule details ›
Chain: A
Length: 226 amino acids
Theoretical weight: 24.6 KDa
Source organism: Streptococcus pneumoniae GA47373
Expression system: Escherichia coli
Structure domains: Histidine kinase-like ATPase, C-terminal domain

Ligands and Environments

1 bound ligand:
Ligand 0R9 1 x 0R9
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: C2221
Unit cell:
a: 73.297Å b: 94.92Å c: 61.247Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.189 0.223
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Multitarget ligands in antibacterial research: progress and opportunities.
East et al. (2013)
3 more

1 mention without citation

A New Class of β-Pyrrolidino-1,2,3-Triazole Derivatives as β-Adrenergic Receptor Inhibitors: Synthesis, Pharmacological, and Docking Studies.
Easwaramoorthi et al. (2019)