X-ray diffraction
2.45Å resolution

Crystal Structure of an M17 aminopeptidase from Trypanosoma Brucei, Tb427tmp.02.4440

Entry authors: Wernimont AK, Osman KT, Loppnau P, Arrowsmith CH, Edwards AM, Bountra C, Hui R, Lin YH, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Cytosol aminopeptidase domain-containing protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 522 amino acids
Theoretical weight: 55.48 KDa
Source organism: Trypanosoma brucei brucei TREU927
Expression system: Escherichia coli
  • Canonical: Q385B0 (Residues: 1-521; Coverage: 100%)
Gene name: Tb11.02.4440
Sequence domains:
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 161.916Å b: 161.74Å c: 176.315Å
α: 90° β: 90° γ: 90°
R R work R free
0.228 0.227 0.253
Expression system: Escherichia coli