4e2e

X-ray diffraction
2.25Å resolution

Crystal structure of a tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide (YWHAG) from Homo sapiens at 2.25 A resolution

Released:
Source organism: Homo sapiens
Entry authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
14-3-3 protein gamma Chain: A
Molecule details ›
Chain: A
Length: 248 amino acids
Theoretical weight: 28.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61981 (Residues: 1-247; Coverage: 100%)
Gene name: YWHAG
Sequence domains: 14-3-3 protein
Structure domains: 14-3-3 domain

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: I222
Unit cell:
a: 60.988Å b: 78.515Å c: 122.131Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.189 0.229
Expression system: Escherichia coli