X-ray diffraction
2.75Å resolution

Crystal Structure of WSN/A Influenza Nucleoprotein with BMS-885986 Ligand Bound

Entry authors: Lewis HA, Baldwin ET, Steinbacher S, Maskos K, Mortl M, Kiefersauer R, Edavettal S, McDonnell PA, Pearce BC, Langley DR

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Nucleoprotein Chains: A, B
Molecule details ›
Chains: A, B
Length: 499 amino acids
Theoretical weight: 56.81 KDa
Source organism: Influenza A virus (A/WSN/1933(H1N1))
Expression system: Escherichia coli
  • Canonical: Q1K9H2 (Residues: 8-498; Coverage: 99%)
Gene name: NP
Sequence domains: Influenza virus nucleoprotein

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P213
Unit cell:
a: 145.496Å b: 145.496Å c: 145.496Å
α: 90° β: 90° γ: 90°
R R work R free
0.254 0.252 0.298
Expression system: Escherichia coli