X-ray diffraction
3.5Å resolution

Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Annexin A2; Protein S100-A10 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 121 amino acids
Theoretical weight: 13.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P60903 (Residues: 1-93; Coverage: 96%)
  • Canonical: P07355 (Residues: 2-16; Coverage: 4%)
Gene names: ANX2, ANX2L4, ANX2LG, ANXA2, CAL1H, CAL1L, CLP11, LPC2D, S100A10
Structure domains: EF-hand
Neuroblast differentiation-associated protein AHNAK Chains: E, F
Molecule details ›
Chains: E, F
Length: 20 amino acids
Theoretical weight: 2.32 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q09666 (Residues: 5654-5673; Coverage: 0%)
Gene names: AHNAK, PM227

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P1
Unit cell:
a: 47.755Å b: 47.791Å c: 62.817Å
α: 71.62° β: 71.63° γ: 68.62°
R R work R free
0.35 0.296 0.327
Expression systems:
  • Escherichia coli
  • Not provided