X-ray diffraction
1.8Å resolution

Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with AWS-I-169


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Envelope glycoprotein gp160 Chains: A, C
Molecule details ›
Chains: A, C
Length: 353 amino acids
Theoretical weight: 39.16 KDa
Source organism: Human immunodeficiency virus type 1 (BRU ISOLATE)
Expression system: Homo sapiens
  • Canonical: Q0ED31 (Residues: 43-486; Coverage: 41%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
Structure domains: Human immunodeficiency virus 1, Gp160, envelope glycoprotein

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 65.443Å b: 68.602Å c: 94.542Å
α: 90° β: 91.38° γ: 90°
R R work R free
0.191 0.19 0.208
Expression system: Homo sapiens