› › Function and Biology

Crystal Structure of Trypanosoma brucei dUTPase with dUpNp and Ca2+

Source organism: Trypanosoma brucei
Biochemical function: metal ion binding
Biological process: not assigned
Cellular component: cytosol

Quick links

EC 3.6.1.23: dUTP diphosphatase

Reaction catalysed:
dUTP + H(2)O = dUMP + diphosphate
Systematic name:
dUTP nucleotidohydrolase
Alternative Name(s):
  • Deoxyuridine-triphosphatase
  • Desoxyuridine 5'-triphosphatase
  • Desoxyuridine 5'-triphosphate nucleotidohydrolase
  • dUTP pyrophosphatase
  • dUTPase

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF08761
Domain description: dUTPase
Occurring in:
  1. Deoxyuridine triphosphatase, putative
The deposited structure of PDB entry 4dkb contains 1 copy of Pfam domain PF08761 (dUTPase) in Deoxyuridine triphosphatase, putative. Showing 1 copy in chain A.

InterPro InterPro annotation
IPR014871
Domain description: dUTPase/dCTP pyrophosphatase
Occurring in:
  1. Deoxyuridine triphosphatase, putative

Structure domain

CATH CATH domain
1.10.4010.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: all-alpha NTP pyrophosphatase fold
Homology: Type II deoxyuridine triphosphatase
Occurring in:
  1. Deoxyuridine triphosphatase, putative
The deposited structure of PDB entry 4dkb contains 1 copy of CATH domain 1.10.4010.10 (all-alpha NTP pyrophosphatase fold) in Deoxyuridine triphosphatase, putative. Showing 1 copy in chain A.

Quick links