X-ray diffraction
3.19Å resolution

Structure of glutamate-GABA antiporter GadC

Source organism: Escherichia coli K-12
Primary publication:
Structure and mechanism of a glutamate-GABA antiporter.
Nature 483 632-6 (2012)
PMID: 22407317

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Glutamate/gamma-aminobutyrate antiporter Chains: A, B
Molecule details ›
Chains: A, B
Length: 511 amino acids
Theoretical weight: 55.11 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
  • Canonical: P63235 (Residues: 1-511; Coverage: 100%)
Gene names: JW1487, acsA, b1492, gadC, xasA
Sequence domains: Amino acid permease

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P212121
Unit cell:
a: 77.618Å b: 105.415Å c: 188.617Å
α: 90° β: 90° γ: 90°
R R work R free
0.311 0.31 0.328
Expression system: Escherichia coli