X-ray diffraction
3.4Å resolution

Structure of the M3 Muscarinic Acetylcholine Receptor


Function and Biology Details

Reaction catalysed:
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Cellular component:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Endolysin; Muscarinic acetylcholine receptor M3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 479 amino acids
Theoretical weight: 54.99 KDa
Source organisms: Expression system: Spodoptera frugiperda
  • Canonical: P08483 (Residues: 57-259, 482-589; Coverage: 53%)
  • Canonical: P00720 (Residues: 1-161; Coverage: 98%)
Gene names: Chrm-3, Chrm3, E
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P1
Unit cell:
a: 54.77Å b: 61.31Å c: 176.91Å
α: 85.87° β: 89.9° γ: 84.9°
R R work R free
0.254 0.251 0.303
Expression system: Spodoptera frugiperda