› 4d94

X-ray diffraction
2.7Å resolution

Crystal Structure of TEP1r

Released:
DOI: 10.2210/pdb4d94/pdb
PDB entry 4d94 coloured by chain, front view.
PDB entry 4d94 coloured by chain, side view.
PDB entry 4d94 coloured by chain, top view.
Source organism: Anopheles gambiae
Primary publication:
Molecular basis for genetic resistance of Anopheles gambiae to Plasmodium: structural analysis of TEP1 susceptible and resistant alleles.
Le BV, Williams M, Logarajah S, Baxter RH
PLoS Pathog 8 e1002958 (2012)
PMID: 23055931

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-111891 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
3 bound ligands:
Ligand NAG 4 x NAG
Ligand CL 1 x CL
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P43212
Unit cell:
a: 150.515Å b: 150.515Å c: 226.315Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.219 0.244
Expression system: Trichoplusia ni

Quick links

Citations

4 review citations

Arthropod Innate Immune Systems and Vector-Borne Diseases.
Baxter et al. (2017)
3 more

4 mentions without citation

Data publication with the structural biology data grid supports live analysis.
Meyer et al. (2016)
3 more