4d2h

X-ray diffraction
1.9Å resolution

Crystal structure of the tetramerisation domain of human CtIP

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA endonuclease RBBP8 Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 38 amino acids
Theoretical weight: 4.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q99708 (Residues: 18-52; Coverage: 4%)
Gene names: CTIP, RBBP8

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P21
Unit cell:
a: 35.97Å b: 37.91Å c: 97.79Å
α: 90° β: 90.02° γ: 90°
R-values:
R R work R free
0.214 0.212 0.251
Expression system: Escherichia coli BL21(DE3)