› 4d1y

X-ray diffraction
2.6Å resolution

Crystal structure of a putative protease from Bacteroides thetaiotaomicron.

Released:
DOI: 10.2210/pdb4d1y/pdb
PDB entry 4d1y coloured by chain, front view.
PDB entry 4d1y coloured by chain, side view.
PDB entry 4d1y coloured by chain, top view.
Source organism: Bacteroides thetaiotaomicron VPI-5482
Primary publication:
Structure and stability of an unusual zinc-binding protein from Bacteroides thetaiotaomicron.
Knaus T, Uhl MK, Monschein S, Moratti S, Gruber K, Macheroux P
Biochim Biophys Acta 1844 2298-305 (2014)
PMID: 25263158

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183752 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein ppBat Chains: A, B
Molecule details ›
Chains: A, B
Length: 200 amino acids
Theoretical weight: 22.1 KDa
Source organism: Bacteroides thetaiotaomicron VPI-5482
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8A8A4 (Residues: 1-175; Coverage: 100%)
Gene name: BT_1263
Sequence domains: DJ-1/PfpI family
Structure domains: Rossmann fold

Ligands and Environments

2 bound ligands:
Ligand RBF 1 x RBF
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: C2
Unit cell:
a: 122.601Å b: 40.851Å c: 71.645Å
α: 90° β: 108.34° γ: 90°
R-values:
R R work R free
0.216 0.214 0.26
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 citations in other articles

SLC39A5 dysfunction impairs extracellular matrix synthesis in high myopia pathogenesis.
Dong et al. (2021)