4d1c

X-ray diffraction
3.7Å resolution

STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH bromovinylhydantoin bound.

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hydantoin permease Chain: A
Molecule details ›
Chain: A
Length: 495 amino acids
Theoretical weight: 54.02 KDa
Source organism: Microbacterium liquefaciens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D6R8X8 (Residues: 1-487; Coverage: 100%)
Gene name: hyuP
Sequence domains: Permease for cytosine/purines, uracil, thiamine, allantoin
Structure domains: Hydantoin permease

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 90.012Å b: 107.323Å c: 109.255Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.26 0.257 0.288
Expression system: Escherichia coli BL21(DE3)