4d0g

X-ray diffraction
2.5Å resolution

Structure of Rab14 in complex with Rab-Coupling Protein (RCP)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ras-related protein Rab-14 Chain: A
Molecule details ›
Chain: A
Length: 175 amino acids
Theoretical weight: 19.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P61106 (Residues: 8-180; Coverage: 81%)
Gene name: RAB14
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Rab11 family-interacting protein 1 Chain: C
Molecule details ›
Chain: C
Length: 69 amino acids
Theoretical weight: 8.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6WKZ4 (Residues: 1216-1283; Coverage: 5%)
Gene names: RAB11FIP1, RCP
Sequence domains: FIP domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2221
Unit cell:
a: 95.87Å b: 148.228Å c: 38.808Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.224 0.294
Expression system: Escherichia coli BL21(DE3)