4cyw

X-ray diffraction
2.6Å resolution

Structure of the A_mallard_Sweden_51_2002 H10 Avian Haemmaglutinin in complex with human receptor analog 6-SLN

Released:
Entry authors: Vachieri SG, Xiong X, Collins PJ, Walker PA, Martin SR, Haire LF, McCauley JW, Gamblin SJ, Skehel JJ

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (6 distinct):
Hemagglutinin Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 324 amino acids
Theoretical weight: 35.32 KDa
Source organism: Influenza A virus (A/mallard/Sweden/51/2002(H10N2))
UniProt:
  • Canonical: E0YNJ7 (Residues: 17-340; Coverage: 58%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains:
Hemagglutinin Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 173 amino acids
Theoretical weight: 19.89 KDa
Source organism: Influenza A virus (A/mallard/Sweden/51/2002(H10N2))
UniProt:
  • Canonical: E0YNJ7 (Residues: 341-513; Coverage: 31%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, GAL, SIA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21
Unit cell:
a: 68.973Å b: 215.446Å c: 79.363Å
α: 90° β: 104.91° γ: 90°
R-values:
R R work R free
0.211 0.208 0.254