Reviews - 4cyo mentioned but not cited (1)
- Structure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT). Salah Ud-Din AI, Tikhomirova A, Roujeinikova A. Int J Mol Sci 17 (2016)
Articles - 4cyo mentioned but not cited (1)
- Structure-based design of potent and selective Leishmania N-myristoyltransferase inhibitors. Hutton JA, Goncalves V, Brannigan JA, Paape D, Wright MH, Waugh TM, Roberts SM, Bell AS, Wilkinson AJ, Smith DF, Leatherbarrow RJ, Tate EW. J. Med. Chem. 57 8664-8670 (2014)
Reviews citing this publication (8)
- Fatty acylation of proteins: The long and the short of it. Resh MD. Prog. Lipid Res. 63 120-131 (2016)
- Lessons from black pepper: piperine and derivatives thereof. Chavarria D, Silva T, Magalhães e Silva D, Remião F, Borges F. Expert Opin Ther Pat 26 245-264 (2016)
- New developments in probing and targeting protein acylation in malaria, leishmaniasis and African sleeping sickness. Ritzefeld M, Wright MH, Tate EW. Parasitology 145 157-174 (2018)
- Pharmacological Inhibition of Protein Lipidation. Ganesan L, Levental I. J. Membr. Biol. 248 929-941 (2015)
- Computational approaches for drug discovery against trypanosomatid-caused diseases. Pereira CA, Sayé M, Reigada C, Silber AM, Labadie GR, Miranda MR, Valera-Vera E. Parasitology 147 611-633 (2020)
- Three-dimensional structures in the design of therapeutics targeting parasitic protozoa: reflections on the past, present and future. Hol WG. Acta Crystallogr F Struct Biol Commun 71 485-499 (2015)
- Drug discovery in leishmaniasis using protein lipidation as a target. Brannigan JA, Wilkinson AJ. Biophys Rev 13 1139-1146 (2021)
- Omics Approaches in Drug Development against Leishmaniasis: Current Scenario and Future Prospects. Rabaan AA, Bakhrebah MA, Mohapatra RK, Farahat RA, Dhawan M, Alwarthan S, Aljeldah M, Al Shammari BR, Al-Najjar AH, Alhusayyen MA, Al-Absi GH, Aldawood Y, Alsaleh AA, Alshamrani SA, Almuthree SA, Alawfi A, Alshengeti A, Alwashmi ASS, Hajissa K, Nassar MS. Pathogens 12 39 (2022)
Articles citing this publication (26)
- Global analysis of protein N-myristoylation and exploration of N-myristoyltransferase as a drug target in the neglected human pathogen Leishmania donovani. Wright MH, Paape D, Storck EM, Serwa RA, Smith DF, Tate EW. Chem. Biol. 22 342-354 (2015)
- Global Profiling and Inhibition of Protein Lipidation in Vector and Host Stages of the Sleeping Sickness Parasite Trypanosoma brucei. Wright MH, Paape D, Price HP, Smith DF, Tate EW. ACS Infect Dis 2 427-441 (2016)
- N-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells. Thinon E, Morales-Sanfrutos J, Mann DJ, Tate EW. ACS Chem. Biol. 11 2165-2176 (2016)
- Discovery of high affinity inhibitors of Leishmania donovani N-myristoyltransferase. Rackham MD, Yu Z, Brannigan JA, Heal WP, Paape D, Barker KV, Wilkinson AJ, Smith DF, Leatherbarrow RJ, Tate EW. Medchemcomm 6 1761-1766 (2015)
- N-myristoyltransferase is a cell wall target in Aspergillus fumigatus. Fang W, Robinson DA, Raimi OG, Blair DE, Harrison JR, Lockhart DE, Torrie LS, Ruda GF, Wyatt PG, Gilbert IH, van Aalten DM. ACS Chem. Biol. 10 1425-1434 (2015)
- Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode. Spinks D, Smith V, Thompson S, Robinson DA, Luksch T, Smith A, Torrie LS, McElroy S, Stojanovski L, Norval S, Collie IT, Hallyburton I, Rao B, Brand S, Brenk R, Frearson JA, Read KD, Wyatt PG, Gilbert IH. ChemMedChem 10 1821-1836 (2015)
- Discovery of pyridyl-based inhibitors of Plasmodium falciparum N-myristoyltransferase. Yu Z, Brannigan JA, Rangachari K, Heal WP, Wilkinson AJ, Holder AA, Leatherbarrow RJ, Tate EW. Medchemcomm 6 1767-1772 (2015)
- Using a non-image-based medium-throughput assay for screening compounds targeting N-myristoylation in intracellular Leishmania amastigotes. Paape D, Bell AS, Heal WP, Hutton JA, Leatherbarrow RJ, Tate EW, Smith DF. PLoS Negl Trop Dis 8 e3363 (2014)
- Profiling of myristoylation in Toxoplasma gondii reveals an N-myristoylated protein important for host cell penetration. Broncel M, Dominicus C, Vigetti L, Nofal SD, Bartlett EJ, Touquet B, Hunt A, Wallbank BA, Federico S, Matthews S, Young JC, Tate EW, Tardieux I, Treeck M. Elife 9 (2020)
- The N-myristoylome of Trypanosoma cruzi. Roberts AJ, Fairlamb AH. Sci Rep 6 31078 (2016)
- A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors. Harrison JR, Brand S, Smith V, Robinson DA, Thompson S, Smith A, Davies K, Mok N, Torrie LS, Collie I, Hallyburton I, Norval S, Simeons FRC, Stojanovski L, Frearson JA, Brenk R, Wyatt PG, Gilbert IH, Read KD. J. Med. Chem. 61 8374-8389 (2018)
- Genetic validation of Leishmania genes essential for amastigote survival in vivo using N-myristoyltransferase as a model. Paape D, Prendergast CT, Price HP, Doehl JSP, Smith DF. Parasit Vectors 13 132 (2020)
- Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani. Corpas-Lopez V, Moniz S, Thomas M, Wall RJ, Torrie LS, Zander-Dinse D, Tinti M, Brand S, Stojanovski L, Manthri S, Hallyburton I, Zuccotto F, Wyatt PG, De Rycker M, Horn D, Ferguson MAJ, Clos J, Read KD, Fairlamb AH, Gilbert IH, Wyllie S. ACS Infect Dis 5 111-122 (2019)
- Structure-guided optimization of quinoline inhibitors of Plasmodium N-myristoyltransferase. Goncalves V, Brannigan JA, Laporte A, Bell AS, Roberts SM, Wilkinson AJ, Leatherbarrow RJ, Tate EW. Medchemcomm 8 191-197 (2017)
- Wheat pathogen Zymoseptoria tritici N-myristoyltransferase inhibitors: on-target antifungal activity and an unusual metabolic defense mechanism. Fedoryshchak RO, Ocasio CA, Strutton B, Mattocks J, Corran AJ, Tate EW. RSC Chem Biol 1 68-78 (2020)
- Collaborative virtual screening to elaborate an imidazo[1,2-a]pyridine hit series for visceral leishmaniasis. Akao Y, Canan S, Cao Y, Condroski K, Engkvist O, Itono S, Kaki R, Kimura C, Kogej T, Nagaoka K, Naito A, Nakai H, Pairaudeau G, Radu C, Roberts I, Shimada M, Shum D, Watanabe NA, Xie H, Yonezawa S, Yoshida O, Yoshida R, Mowbray C, Perry B. RSC Med Chem 12 384-393 (2021)
- Enantioseparation of 3-Hydroxycarboxylic Acids via Diastereomeric Salt Formation by 2-Amino-1,2-diphenylethanol (ADPE) and Cinchonidine. Chandrasekaran S, Tambo M, Yamazaki Y, Muramatsu T, Kanda Y, Hirose T, Kodama K. Molecules 28 114 (2022)
- Exploring Novel N-Myristoyltransferase Inhibitors: A Molecular Dynamics Simulation Approach. Khalil R, Ashraf S, Khalid A, Ul-Haq Z. ACS Omega 4 13658-13670 (2019)
- Hit-to-lead optimization of a benzene sulfonamide series for potential antileishmanial agents. Koovits PJ, Dessoy MA, Matheeussen A, Maes L, Caljon G, Ferreira LLG, Chelucci RC, Michelan-Duarte S, Andricopulo AD, Campbell S, Kratz JM, Mowbray CE, Dias LC. RSC Med Chem 11 1267-1274 (2020)
- Identification of Potential Leishmania N-Myristoyltransferase Inhibitors from Withania somnifera (L.) Dunal: A Molecular Docking and Molecular Dynamics Investigation. Orabi MAA, Alshahrani MM, Sayed AM, Abouelela ME, Shaaban KA, Abdel-Sattar ES. Metabolites 13 93 (2023)
- Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development. Fenwick MK, Reers AR, Liu Y, Zigweid R, Sankaran B, Shin J, Hulverson MA, Hammerson B, Fernández Álvaro E, Myler PJ, Kaushansky A, Van Voorhis WC, Fan E, Staker BL. ACS Infect Dis 9 1821-1833 (2023)
- Novel Thienopyrimidine Inhibitors of Leishmania N-Myristoyltransferase with On-Target Activity in Intracellular Amastigotes. Bell AS, Yu Z, Hutton JA, Wright MH, Brannigan JA, Paape D, Roberts SM, Sutherell CL, Ritzefeld M, Wilkinson AJ, Smith DF, Leatherbarrow RJ, Tate EW. J Med Chem 63 7740-7765 (2020)
- Screening of medicinal plants unraveled the leishmanicidal credibility of Garcinia cowa; highlighting Norcowanin, a novel anti-leishmanial phytochemical through in-silico study. Pyne N, Paul S. J Parasit Dis 46 202-214 (2022)
- Structure-Guided Identification of Resistance Breaking Antimalarial N‑Myristoyltransferase Inhibitors. Schlott AC, Mayclin S, Reers AR, Coburn-Flynn O, Bell AS, Green J, Knuepfer E, Charter D, Bonnert R, Campo B, Burrows J, Lyons-Abbott S, Staker BL, Chung CW, Myler PJ, Fidock DA, Tate EW, Holder AA. Cell Chem Biol 26 991-1000.e7 (2019)
- Synthesis of 3-Substituted Pyrrolidines via Palladium-Catalyzed Hydroarylation. Sweeney JB, Doulcet J, Thapa B. iScience 9 328-336 (2018)
- Virtual screening to identify Leishmania braziliensis N-myristoyltransferase inhibitors: pharmacophore models, docking, and molecular dynamics. de Carvalho Gallo JC, de Mattos Oliveira L, Araújo JSC, Santana IB, Dos Santos Junior MC. J Mol Model 24 260 (2018)