4cvh

X-ray diffraction
2.39Å resolution

Crystal structure of human isoprenoid synthase domain-containing protein

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
D-ribitol-5-phosphate cytidylyltransferase Chain: A
Molecule details ›
Chain: A
Length: 411 amino acids
Theoretical weight: 46.11 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: A4D126 (Residues: 43-451; Coverage: 91%)
Gene names: CRPPA, ISPD
Sequence domains:
Structure domains: Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: C2221
Unit cell:
a: 79.36Å b: 116.8Å c: 111.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.189 0.244
Expression system: Spodoptera frugiperda