4csk

X-ray diffraction
3.28Å resolution

human Aquaporin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aquaporin-1 Chain: A
Molecule details ›
Chain: A
Length: 292 amino acids
Theoretical weight: 31.17 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P29972 (Residues: 1-269; Coverage: 100%)
Gene names: AQP1, CHIP28
Sequence domains: Major intrinsic protein
Structure domains: Glycerol uptake facilitator protein.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: I422
Unit cell:
a: 89.28Å b: 89.28Å c: 174.85Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.234 0.298
Expression system: Spodoptera frugiperda