4cr0

X-ray diffraction
2.65Å resolution

Crystal Structure of H5 (VN1194) Asn186Lys/Gly143Arg Mutant Haemagglutinin

Released:
Entry authors: Collins PJ, Vachieri SG, Xiong X, Xiao H, Martin SR, Coombs PJ, Liu J, Walker PA, Lin YP, McCauley JW, Gamblin SJ, Skehel JJ

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemagglutinin Chain: A
Molecule details ›
Chain: A
Length: 326 amino acids
Theoretical weight: 37.07 KDa
Source organism: Influenza A virus (A/Vietnam/1194/2004(H5N1))
Expression system: Gallus gallus
UniProt:
  • Canonical: Q6DQ34 (Residues: 17-342; Coverage: 58%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains:
Hemagglutinin Chain: B
Molecule details ›
Chain: B
Length: 166 amino acids
Theoretical weight: 19.09 KDa
Source organism: Influenza A virus (A/Vietnam/1194/2004(H5N1))
Expression system: Gallus gallus
UniProt:
  • Canonical: Q6DQ34 (Residues: 347-512; Coverage: 29%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P63
Unit cell:
a: 77.95Å b: 77.95Å c: 210.411Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.227 0.224 0.262
Expression system: Gallus gallus