Function and Biology

Crystal structure of PQBP1 bound to spliceosomal U5-15kD

Source organism: Homo sapiens
Biochemical function: protein binding
Biological process: cell division
Cellular component: U2-type precatalytic spliceosome

Sequence family

Pfam Protein family (Pfam)
PF02966
Domain description: Mitosis protein DIM1
Occurring in:
  1. Polyglutamine-binding protein 1; Thioredoxin-like protein 4A
The deposited structure of PDB entry 4cdo contains 2 copies of Pfam domain PF02966 (Mitosis protein DIM1) in Polyglutamine-binding protein 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR004123
Domain description: Dim1 family
Occurring in:
  1. Polyglutamine-binding protein 1; Thioredoxin-like protein 4A
IPR036249
Domain description: Thioredoxin-like superfamily
Occurring in:
  1. Polyglutamine-binding protein 1; Thioredoxin-like protein 4A

Structure domain

CATH CATH domain
3.40.30.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Glutaredoxin
Homology: Glutaredoxin
Occurring in:
  1. Polyglutamine-binding protein 1; Thioredoxin-like protein 4A
The deposited structure of PDB entry 4cdo contains 2 copies of CATH domain 3.40.30.10 (Glutaredoxin) in Polyglutamine-binding protein 1. Showing 1 copy in chain A.