4cb4

X-ray diffraction
1.6Å resolution

Structure of Influenza A H5N1 PB2 cap-binding domain with bound m7GTP

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polymerase basic protein 2 Chain: A
Molecule details ›
Chain: A
Length: 167 amino acids
Theoretical weight: 18.89 KDa
Source organism: Influenza A virus (A/duck/Shantou/4610/2003(H5N1))
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q2LG68 (Residues: 318-483; Coverage: 22%)
Gene name: PB2
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PB2

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P65
Unit cell:
a: 82.48Å b: 82.48Å c: 55.24Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.128 0.126 0.17
Expression system: Escherichia coli BL21