4cay

X-ray diffraction
1.48Å resolution

Crystal structure of a human Anp32e-H2A.Z-H2B complex

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
Non-polymer only trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Histone H2A.Z Chain: A
Molecule details ›
Chain: A
Length: 111 amino acids
Theoretical weight: 12.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0C0S5 (Residues: 19-128; Coverage: 86%)
Gene names: H2AFZ, H2AZ, H2AZ1
Sequence domains: C-terminus of histone H2A
Structure domains: Histone, subunit A
Histone H2B type 1-J Chain: B
Molecule details ›
Chain: B
Length: 97 amino acids
Theoretical weight: 10.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P06899 (Residues: 31-126; Coverage: 76%)
Gene names: H2BC11, H2BFR, HIST1H2BJ
Structure domains: Histone, subunit A
Acidic leucine-rich nuclear phosphoprotein 32 family member E Chain: C
Molecule details ›
Chain: C
Length: 30 amino acids
Theoretical weight: 3.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9BTT0 (Residues: 215-240; Coverage: 10%)
Gene name: ANP32E

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P21
Unit cell:
a: 31.816Å b: 66.076Å c: 45.293Å
α: 90° β: 95.76° γ: 90°
R-values:
R R work R free
0.169 0.168 0.195
Expression system: Escherichia coli BL21(DE3)