X-ray diffraction
1.8Å resolution

Legionella pneumophila NTPDase1 crystal form I, open, AMPNP complex

Source organism: Legionella pneumophila
Entry authors: Zebisch M, Schaefer P, Lauble P, Straeter N

Function and Biology Details

Reaction catalysed:
(1a) a nucleoside 5'-triphosphate + H(2)O = a nucleoside 5'-diphosphate + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Ectonucleoside triphosphate diphosphohydrolase I Chain: A
Molecule details ›
Chain: A
Length: 365 amino acids
Theoretical weight: 41.54 KDa
Source organism: Legionella pneumophila
Expression system: Escherichia coli
  • Canonical: Q5ZUA2 (Residues: 37-393; Coverage: 91%)
Gene name: lpg1905
Sequence domains: GDA1/CD39 (nucleoside phosphatase) family
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P321
Unit cell:
a: 102.853Å b: 102.853Å c: 74.779Å
α: 90° β: 90° γ: 120°
R R work R free
0.164 0.163 0.209
Expression system: Escherichia coli