PDBe 4bla

X-ray diffraction
3.5Å resolution

Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory subdomain (crystal form II)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Maltose/maltodextrin-binding periplasmic protein; Suppressor of fused homolog Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 756 amino acids
Theoretical weight: 84.05 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Best match: P0AEX9 (Residues: 27-393)
  • Best match: Q9UMX1 (Residues: 32-278, 361-483)
Gene names: JW3994, SUFU, UNQ650/PRO1280, b4034, malE

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P21212
Unit cell:
a: 117.92Å b: 372.57Å c: 86.25Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.261 0.259 0.293
Expression system: Escherichia coli BL21(DE3)