PDBe 4bl9

X-ray diffraction
2.8Å resolution

Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory subdomain (crystal form I)


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Maltose/maltodextrin-binding periplasmic protein; Suppressor of fused homolog Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 756 amino acids
Theoretical weight: 84.05 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
  • Best match: P0AEX9 (Residues: 27-393)
  • Best match: Q9UMX1 (Residues: 32-278, 361-483)
Gene names: JW3994, SUFU, UNQ650/PRO1280, b4034, malE

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P1
Unit cell:
a: 93.43Å b: 103.28Å c: 111.51Å
α: 63.67° β: 81.13° γ: 76.03°
R R work R free
0.201 0.2 0.234
Expression system: Escherichia coli BL21(DE3)